The Medical Letter on Drugs and Therapeutics
Addendum: Tramadol as an NSAID Alternative
Med Lett Drugs Ther. 2005 Feb 14;47(1202):16
 Select a term to see related articles  Analgesia   Analgesics   NSAIDs   pain   tramadol   Ultram 

In our January 17 issue, a short article on NSAID alternatives mentioned that tramadol (Ultram, and others), a weak opioid analgesic, could be helpful for some patients. A few readers have commented that we should have said something about its drawbacks. The need for slow titration in dosage limits the drug's use for treatment of acute pain. Seizures have been reported with tramadol; patients taking an antidepressant or an antipsychotic drug may be at increased risk. Tramadol is not a controlled substance, but psychological and physical dependence have occurred.

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