The Medical Letter on Drugs and Therapeutics
FROM
ISSUE1748
ISSUE1748
February 16, 2026
Sebetralstat (Ekterly) for Treatment of Hereditary Angioedema Attacks
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Sebetralstat (Ekterly) for Treatment of Hereditary Angioedema Attacks
February 16, 2026 (Issue: 1748)
Sebetralstat (Ekterly – Kalvista), an oral plasma
kallikrein inhibitor, has been approved by the FDA
for treatment of acute hereditary angioedema (HAE)
attacks in patients ≥12 years old. It is the first oral
drug to be approved in the US for...more
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