The Medical Letter on Drugs and Therapeutics
FROM
ISSUE1754
ISSUE1754
May 11, 2026
Leucovorin for Cerebral Folate Deficiency
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Leucovorin for Cerebral Folate Deficiency
May 11, 2026 (Issue: 1754)
The FDA has approved use of oral leucovorin calcium (folinic
acid) for treatment of cerebral folate transport deficiency in
patients who have a confirmed variant in the folate receptor 1
gene (FOLR1-CFTD). It is the first drug to be approved for...more
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