The Medical Letter on Drugs and Therapeutics
FROM
ISSUE1744
ISSUE1744
December 22, 2025
A Dihydroergotamine Autoinjector (Brekiya) for Migraine
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A Dihydroergotamine Autoinjector (Brekiya) for Migraine
December 22, 2025 (Issue: 1744)
The FDA has approved Brekiya (Amneal), the first
dihydroergotamine (DHE) autoinjector product.
DHE has been available for IV, IM, SC and intranasal
administration (Trudhesa, and others). Like other
parenteral DHE products, Brekiya is indicated...more
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